Islam in Syria comprises 87% of the total population. Sunnis make up 74% of the total, mostly of Arab, Kurdish and Turkish ethnicities.

Shia's make up the remaining 13%: Alawites, Ismailis, and Twelvers. Alawites are the pre-dominant Shia group, followed by Twelvers and Ismailis. Sunnis are mainly of the Shafi'i madhhab with pockets of Hanafi and Hanbali. Several large Sufi orders are active in the country, including the Naqshbandi tariqa, and Qadiriyya. Although not traditionally considered as Muslims, the Druze make up 3% of the total population.

The Umayyad Mosque, also known as the Great Mosque of Damascus located in the old city of Damascus, is one of the largest and oldest mosques in the world. It is considered the fourth-holiest place in Islam.

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